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"There is an urgent need to improve the drug development process and to enhance collaboration among the Government, Industry, and Academia."

– FDA study to Congress

Source: New Drug Development: Science, Business, Regulatory, and Intellectual Property Issues Cited as Hampering Drug Development Efforts, 2006 FDA study to Congress

NCI's Advanced Technology Partnerships Initiative

Mission

To accelerate the delivery of new products to cancer patients using a novel business/research model, advanced technologies, and effective public/private partnerships. Establish opportunities for collocation of synergistic biomedical research institutions and life science companies. Enable access to world-class technologies, capabilities, and scientific expertise in Cancer & HIV translational R&D through strategic partnerships.

Overview

  • Initiated in 2007 as part of a National Cancer Institute strategic imperative
  • Partnerships accomplished through FFRDC in Frederick, Maryland- a government-owned, contractor-operated national laboratory
  • Includes in-reach activity to NCI programs and outreach activity to industry and academia

Benefits

  • Designed to reduce time and cost associated with the translation of candidate drug products into effective interventions
  • Utilize technology platforms to help partners allocate finite resources to high-probability candidates and move more rapidly through development and clinical testing
  • Enables studies that partners my otherwise be unable to accomplish
  • Access to diverse and integrated portfolio of cost-effective, state-of-the-art advanced technology platforms and to translational and clinical drug development expertise, distinct from drug discovery paradigm
  • Expanded access to cGMP development and manufacturing capabilities and regulatory affairs support

Contractual Agreements

Core Research Strengths

  • Flexible business mechanisms and contractual agreements such as:
    • Material Transfer Agreements (MTA)
    • Collaboration Agreements
    • Testing Agreements
      (platform technology development)
    • Cooperative Research & Development Agreements (CRADA)
    • Clinical Trial CRADAs (CT-CRADA)
    • Clinical Trial Agreements (CTA)
    • Small Business Innovative Research (SBIR) and
    • Small Business Technology Transfer (STTR) Support
    • Guest Researcher Agreements
    • Technology transfer and commercialization opportunities
  • Biopharmaceutical Development
    • Moving early drug candidates from concept to clinic
  • Proteins and Proteomics
    • Expertise in macromolecular interactions
    • Innovative solutions for access to proteins
    • Proteomics discoveries through enabling technologies
    • Specialty services in viral-based applications
  • Imaging and Nanotechnology
    • New applications in cancer therapeutics and diagnostics
    • Cellular and molecular imaging expertise
  • Integrated In Vivo Services
    • Advanced translational research
  • Advanced Biomedical Computing
    • High-performance bioinformatics and modeling support
  • Genetics and Genomics
    • Systematic R&D in a high-throughput environment

Source: www.atpihome.com

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